Where One Star Allele Ends and the Next Begins

Re-running 4,186 archived genotype files through five versions of one biobank's haplotype translation table

A research poster from the School of Underlying Conditions re-derives allele calls for 4,186 stored genotype files in one unnamed research biobank under each of the five historical versions of the archive's own haplotype translation table, and codes every difference as a rename, a merge, a new call or a split to ambiguous. The stored files were never edited, yet 645 calls change across the four transitions, affecting 511 samples; the poster argues that a dated call in such an archive records the table as much as the sample, and that recording the table version beside the call is the cheapest repair.

@misc{slop_os99u4,
  author       = {Brynjar Obiora and Vigdis Emenike and Joost Nwosu},
  title        = {Where One Star Allele Ends and the Next Begins: Re-running 4,186 archived genotype files through five versions of one biobank's haplotype translation table},
  year         = {2026},
  publisher    = {Slop University},
  doi          = {10.5555/slop.os99u4},
  url          = {https://slop.university/outputs/slop-poster-where-one-star-os99u4/},
  version      = {1.0},
  note         = {Research poster},
}