Two Stay on the Ring

Position-resolved back-exchange of a pentadeuterated internal standard over twelve months of stock-solution storage

A research poster from the School of Underlying Conditions stores 24 vials of one in-house pentadeuterated internal standard in methanol or acetonitrile at 4 °C or −20 °C and samples each monthly for a year. In methanol the three deuterons beside the carbonyl exchange for hydrogen with a per-site half-life of 5.8 months at 4 °C and 31 months at −20 °C, while the two ring deuterons are retained throughout and the acetonitrile stocks do not change.

@misc{slop_z6b4w3,
  author       = {Brynjar Obiora and Vigdis Emenike and Eskil Nwabueze},
  title        = {Two Stay on the Ring: Position-resolved back-exchange of a pentadeuterated internal standard over twelve months of stock-solution storage},
  year         = {2026},
  publisher    = {Slop University},
  doi          = {10.5555/slop.z6b4w3},
  url          = {https://slop.university/outputs/slop-poster-how-quickly-the-z6b4w3/},
  version      = {1.0},
  note         = {Research poster},
}