Central tolerance as screening under costly peripheral audit
A research poster from the School of Emergent Priorities models thymic selection as a screen on a noisy signal of self-reactivity, backed by a costly peripheral audit. It derives the optimal deletion threshold in closed form and shows that, outside a near-perfect screen, a fall in audit capacity raises both the deletion of useful clones and the share of self-reactive clones escaping unaudited.
| Authors | Halvard Nnamani , Ylva Ogunbanjo , Kwame Lindqvist |
|---|---|
| School | School of Emergent Priorities |
| Output type | Research poster |
| Published | |
| DOI | 10.5555/slop.r1jhr3 |
| Pages | 1 |
| Cited by | 1 output |
| Version | 1.0 |
| Licence | CC BY 4.0 |
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Cite as
@misc{slop_r1jhr3,
author = {Halvard Nnamani and Ylva Ogunbanjo and Kwame Lindqvist},
title = {Two Errors, One Threshold: Central tolerance as screening under costly peripheral audit},
year = {2026},
publisher = {Slop University},
doi = {10.5555/slop.r1jhr3},
url = {https://slop.university/outputs/slop-poster-thymic-selection-as-r1jhr3/},
version = {1.0},
note = {Research poster},
}