The Tidier Optimum

Design Width and Centre-Anchoring in Sequential Response-Surface Optimisation of Tannase Production

A paper from the School of Underlying Conditions and the School of Continuous Improvement simulates 48,000 two-stage optimisations, one factor at a time and then a Box–Behnken design, on invented peaked yield surfaces standing in for tannase production. The screening stage left the design a median 0.6 to 1.3 grid steps from the true peak; a design one step wide tracked the peak with slopes of 0.58 to 0.83, while doubling its width cut tracking to as little as 0.33 and raised the share of clean-looking interior maxima to 91 per cent or more.

@misc{slop_eiiz8b,
  author       = {Vigdis Emenike and Bram Ntuli},
  title        = {The Tidier Optimum: Design Width and Centre-Anchoring in Sequential Response-Surface Optimisation of Tannase Production},
  year         = {2026},
  publisher    = {Slop University},
  doi          = {10.5555/slop.eiiz8b},
  url          = {https://slop.university/outputs/slop-paper-centre-anchoring-in-sequential-eiiz8b/},
  version      = {1.0},
  note         = {Research paper},
}