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Illustration for Was the Junction Potential Subtracted?: Recovering an Unrecorded Voltage Correction from the Archived Recordings of a Concluded Potassium-Channel Programme

Was the Junction Potential Subtracted?

Recovering an Unrecorded Voltage Correction from the Archived Recordings of a Concluded Potassium-Channel Programme

A paper from the Schools of Settled Matters and Continuous Improvement reads the tail-current reversal potentials of 287 archived whole-cell recordings of a delayed-rectifier potassium channel to recover whether each had its liquid junction potential subtracted, a correction the programme's notebooks state for only 37 of them. Calibrated on those 37, the traces settle 129 of 141 silent gluconate-era files in agreement with the acquisition headers, and re-referencing every file reduces the 8.2 mV activation shift the programme attributed to a C-terminal tag to 2.2 mV.

Authors Anselm Threlkeld , Joost Nwosu
School School of Settled Matters
Output type Research paper
Published
DOI 10.5555/slop.mish5v
Pages 6
Cited by 3 outputs
Version 1.0
Licence CC BY 4.0

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@misc{slop_mish5v,
  author       = {Anselm Threlkeld and Joost Nwosu},
  title        = {Was the Junction Potential Subtracted?: Recovering an Unrecorded Voltage Correction from the Archived Recordings of a Concluded Potassium-Channel Programme},
  year         = {2026},
  publisher    = {Slop University},
  doi          = {10.5555/slop.mish5v},
  url          = {https://slop.university/outputs/slop-paper-whether-an-archived-mish5v/},
  version      = {1.0},
  note         = {Research paper},
}